@misc{10481/61812,
year = {2018},
month = {6},
url = {http://hdl.handle.net/10481/61812},
abstract = {Background The CUN-BAE (Clínica Universidad de Navarra-Body adiposity estimator) index is an anthropometric index
based on age, sex and body mass index (BMI) for a refined prediction of body fatness in adults. CUN-BAE may help detect
metabolically unhealthy individuals with otherwise normal weight according to BMI or waist circumference (WC). The aim
of this study was to evaluate whether CUN-BAE, independent of its components (BMI, age and sex), was associated with
cardiometabolic conditions including arterial hypertension, diabetes mellitus and metabolic syndrome (MetS).
Methods The ENRICA study was based on a cross-sectional sample of non-institutionalized men and women representative
of the adult Spanish population. Body weight, height, and WC were measured in all participants. The residual of CUN-BAE
(rCUN-BAE), i.e. the part of the index not explained by its components, was calculated. The associations of CUN-BAE,
rCUN-BAE, BMI and WC with hypertension, diabetes and MetS were analysed by multivariate logistic regression, and the
Akaike information criterion (AIC) was calculated.
Results The sample included 12,122 individuals. rCUN-BAE was associated with hypertension (OR 1.14, 95% CI 1.07–1.21)
and MetS (OR 1.48, 1.37–1.60), but not with diabetes (OR 1.05, 0.94–1.16). In subjects with a BMI < 25 kg/m2, CUN-BAE
was significantly associated with all three outcome variables. CUN-BAE was more strongly associated with the cardiometabolic
conditions than BMI and WC and fit similar AICs.
Conclusions The CUN-BAE index for body fatness was positively associated with hypertension, diabetes and MetS in adults
independent of BMI or WC. CUN-BAE may help to identify individuals with cardiometabolic conditions beyond BMI, but
this needs to be confirmed in prospective settings.},
organization = {The ENRICA study was funded and financed by Sanofi-
Aventis. Specific funding for this analysis came from the governmental
Spain FIS PI12/1166 and PI11/01379 projects and from the “UAM
Chair in Epidemiology and Control of Cardiovascular Risk”.},
publisher = {Springer Nature},
keywords = {Body fatness},
keywords = {Metabolic syndrome},
keywords = {Hypertension},
keywords = {Diabetes},
title = {Net contribution and predictive ability of the CUN-BAE body fatness index in relation to cardiometabolic conditions},
doi = {10.1007/s00394-018-1743-9},
author = {Davila Batista, Verónica and Olmedo Requena, María Rocío},
}