@misc{10481/61791,
year = {2020},
month = {2},
url = {http://hdl.handle.net/10481/61791},
abstract = {The method used to select representative gas exchange data from large datasets influences
the resting metabolic rate (RMR) returned. This study determines which of three methods yields the
lowest RMR (as recommended for use in human energy balance studies), and in which method the
greatest variance in RMR is explained by classical determinants of this variable. A total of 107 young
and 74 middle-aged adults underwent a 30 min RMR examination using a breath-by-breath metabolic
cart. Three gas exchange data selection methods were used: (i) steady state (SSt) for 3, 4, 5, or 10 min,
(ii) a pre-defined time interval (TI), i.e., 6–10, 11–15, 16–20, 21–25, 26–30, 6–25, or 6–30 min, and (iii)
“filtering”, setting thresholds depending on the mean RMR value obtained. In both cohorts, the RMRs
yielded by the SSt and filtering methods were significantly lower (p < 0.021) than those yielded by the
TI method. No differences in RMR were seen under the different conditions of the SSt method, or of
the filtering method. No differences were seen between the methods in terms of the variance in RMR
explained by its classical determinants. In conclusion, the SSt and filtering methods return the lowest
RMRs and intra-measurement coefficients of variation when using breath-by-breath metabolic carts.},
organization = {This study was supported by the Spanish Ministry of Economy and Competitiveness via the Fondo
de Investigación Sanitaria del Instituto de Salud Carlos III (PI13/01393), Retos de la Sociedad (DEP2016-79512-R) and
European Regional Development Funds (ERDF), the Spanish Ministry of Education (FPU 15/04059 and FPU14/04172),
the Fundación Iberoamericana de Nutrición (FINUT), the Redes Temáticas de Investigación Cooperativa RETIC (Red
SAMID RD16/0022), the AstraZeneca HealthCare Foundation, the University of Granada Plan Propio de Investigación
2016 Excellence Actions: Unit of Excellence on Exercise and Health (UCEES) and Plan Propio de Investigación 2018
and 2019 Programa Contratos-Puente and Plan Propio de Investigación 2018 Programa Perfeccionamiento de Doctores, and
the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades (ERDF: ref. SOMM17/6107/UGR),
and the Fundación Alfonso Martín Escudero.},
publisher = {MDPI},
keywords = {Resting energy expenditure},
keywords = {Indirect calorimetry},
keywords = {Macronutrient oxidation},
title = {Impact of the Method Used to Select Gas Exchange Data for Estimating the Resting Metabolic Rate, as Supplied by Breath-by-Breath Metabolic Carts},
doi = {10.3390/nu12020487},
author = {Alcántara Alcántara, Juan Manuel and Sánchez-Delgado, Guillermo and Amaro Gahete, Francisco José and Galgani, José E. and Ruiz Ruiz, Jonatan},
}