@misc{10481/61665,
year = {2019},
url = {http://hdl.handle.net/10481/61665},
abstract = {The present study examines whether the daily rhythm of distal skin
temperature (DST) is associated with brown adipose tissue (BAT) metabolism
as determined by 18F-fluorodeoxyglucose (18F-FDG) uptake in young adults.
Using a wireless thermometer (iButton) worn on the nondominant wrist, DST
was measured in 77 subjects (26% male; age 22 ± 2 years; body mass index 25.2
± 4.8 kg/m2) for 7 consecutive days. The temperatures to which they were
habitually exposed over the day were also recorded. The interday stability of
DST was calculated from the collected data, along with the intraday variability
and relative amplitude; the mean temperature of the 5 and 10 consecutive
hours with the maximum and minimum DST values, respectively; and when
these hours occurred. Following exposure to cold, BAT volume and mean and
peak standardized 18F-FDG uptake (SUVmean and SUVpeak) were determined for
each subject via static 18F-FDG positron emission tomography/computed
tomography scanning. Relative amplitude and the time at which the 10 consecutive
hours of minimum DST values occurred were positively associated
with BAT volume, SUVmean, and SUVpeak (p ≤ 0.02), whereas the mean DST of
that period was inversely associated with the latter BAT variables (p ≤ 0.01).
The interday stability and intraday variability of the DST were also associated
(directly and inversely, respectively) with BAT SUVpeak (p ≤ 0.02 for both). All
of these associations disappeared, however, when the analyses were adjusted
for the ambient temperature to which the subjects were habitually exposed. Thus, the relationship between the daily rhythm of DST and BAT activity estimated
by 18F-FDG uptake is masked by environmental and likely behavioral
factors. Of note is that those participants exposed to the lowest ambient temperature
showed 3 to 5 times more BAT volume and activity compared with
subjects who were exposed to a warmer ambient temperature.},
publisher = {SAGE Publications},
keywords = {Brown fat},
keywords = {Circadian rhythms},
keywords = {Wrist skin temperature},
keywords = {Glucose uptake},
keywords = {Obesity},
keywords = {Cardiometabolic risk},
keywords = {Cold-induced thermogenesis},
title = {Relationship between the Daily Rhythm of Distal Skin Temperature and Brown Adipose Tissue 18F-FDG Uptake in Young Sedentary Adults},
doi = {10.1177/0748730419865400},
author = {Acosta Manzano, Francisco Miguel and Martínez Téllez, Borja Manuel and Blondin, Denis P. and Haman, François and Rensen, Patrick C. N. and Llamas Elvira, José Manuel and Martínez-Nicolás, Antonio and Ruiz Ruiz, Jonatan},
}