@misc{10481/61571,
year = {2019},
month = {3},
url = {http://hdl.handle.net/10481/61571},
abstract = {Sclerocarya birrea is a tree indigenous to Southern Africa with significant importance in
rural livelihoods for food, medicine, and carving. The bark, which contains 10–20% tannin, provides
several pharmacological benefits as an antidiabetic, anti-inflammatory, antimicrobial, anti-atherogenic,
and antioxidant medication, among others. This study compared different extraction techniques
used to recover bioactive compounds from marula bark. For this purpose, solid–liquid extraction,
supercritical fluid extraction (SFE), and pressurized liquid extraction (PLE) were performed under
selected conditions, using only “food-grade” solvents. The potential use of the proposed extraction
methodologies was evaluated in term of yield, and the individual phenolic composition determined
by HPLC–ESI–TOF–MS. PLE provided a high extraction yield in all experimental conditions. With
regard to bioactive compounds composition, a total of 71 compounds, a significant percentage of
which in a galloyl form, were distributed in five major categories. The largest number of compounds,
mostly flavonoid aglycones, were extracted by PLE, generally when the extraction was developed
at low temperatures. SFE did prove effective as a way of extracting antidiabetic proanthocyanidins.
Advanced extraction techniques represent a powerful tool to obtain bioactive compounds from
S. birrea bark, which can be used as supplements or food ingredients, promoting the valorization of
this crop.},
organization = {This work was supported by the project AGL2015-67995-C3-2-R (Spanish Ministry of Science and
Innovation) as well as P11-CTS-7625 (Andalusian Regional Government Council of Innovation and Science) and
The European Social Fund (FSE) for the contract PTQ-13-06429.},
publisher = {MDPI},
keywords = {Sclerocarya birrea},
keywords = {Bark},
keywords = {Green extraction},
keywords = {Proanthocyanidins},
keywords = {PLE},
title = {Enhancing the Yield of Bioactive Compounds from Sclerocarya birrea Bark by Green Extraction Approaches},
doi = {10.3390/molecules24050966},
author = {Cádiz Gurrea, María de la Luz and Lozano Sánchez, Jesús and Fernández Ochoa, Álvaro and Segura Carretero, Antonio},
}