@misc{10481/61205,
year = {2020},
month = {2},
url = {http://hdl.handle.net/10481/61205},
abstract = {OBJECTIVES: To summarize the literature on the influence of exercise on the gut microbiota of healthy adults.
METHODS: A systematic and comprehensive search in electronic database, including SciELO, Scopus, PubMed,
and Web of Science up to July 5, 2019. Eligibility criterion was original studies conducted on healthy
humans including exercise interventions or interventions involving any type of physical activity.
RESULTS: The initial search retrieved 619 articles of which 18 met the inclusion criteria, 9 were observational,
4 reported very short-term exercise interventions, and 5 reported medium/long-term exercise
interventions. Higher levels of physical activity or cardiorespiratory fitness were positively associated
with fecal bacterial alpha diversity. Contrasting associations were detected between both the level of
physical activity and cardiorespiratory fitness and fecal counts for the phyla Firmicutes, Bacteroidetes,
and Proteobacteria. Higher levels of physical activity and cardiorespiratory fitness were positively
associated with the fecal concentration of short-chain fatty acids. Reports on the effects of very shortterm
and medium/long-term exercise interventions on the composition of the gut microbiota were
inconsistent.
DISCUSSION: Higher levels of physical activity and cardiorespiratory fitness are associated with higher fecal bacterial
alpha diversity and with the increased representation of some phyla and certain short-chain fatty acids
in the feces of healthy adults. Very short-term and medium/long-term exercise interventions seem to
influence the fecal counts of some phyla. However, the heterogeneity between studies hampers any
strong conclusions from being drawn. Better-designed studies are needed to unravel the possible
mechanisms through which exercise might influence the composition and activity of the human gut
microbiota.},
organization = {The study was funded by the Spanish Ministry of Economy and Competitiveness via the Fondo de Investigación Sanitaria del Instituto de Salud Carlos III (PI13/01393), Retos de la Sociedad (DEP2016-79512-R), and European Regional Development Funds (ERDF), by the Spanish Ministry of Education (FPU 16/05159 and FPU17/01523), the Fundación Iberoamericana de Nutrición (FINUT), the Redes Temáticas De Investigación Cooperativa RETIC (Red SAMID RD16/0022), AstraZeneca HealthCare Foundation, the University of Granada Plan Propio de Investigación 2016 (Excellence actions: Unit of Excellence on Exercise and Health [UCEES]), and by the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades (ERDF, SOMM17/ 6107/UGR). B.M.-T. is supported by individual postdoctoral grants from the Fundación Alfonso Martin Escudero.},
publisher = {Lippincott, Williams & Wilkins},
title = {Influence of Exercise on the Human Gut Microbiota of Healthy Adults: A Systematic Review},
doi = {10.14309/ctg.0000000000000126},
author = {Ortiz-Alvarez, Lourdes and Xu, Huiwen and Martínez Téllez, Borja Manuel},
}