@misc{10481/59924,
year = {2019},
month = {2},
url = {http://hdl.handle.net/10481/59924},
abstract = {The Alteromonas stellipolaris strains PQQ-42 and PQQ-44, previously isolated from a fish hatchery,
have been selected on the basis of their strong quorum quenching (QQ) activity, as well as their ability
to reduce Vibrio-induced mortality on the coral Oculina patagonica. In this study, the genome sequences
of both strains were determined and analyzed in order to identify the mechanism responsible for QQ
activity. Both PQQ-42 and PQQ-44 were found to degrade a wide range of N-acylhomoserine lactone
(AHL) QS signals, possibly due to the presence of an aac gene which encodes an AHL amidohydrolase. In
addition, the different colony morphologies exhibited by the strains could be related to the differences
observed in genes encoding cell wall biosynthesis and exopolysaccharide (EPS) production. The PQQ-42
strain produces more EPS (0.36 g l−1) than the PQQ-44 strain (0.15 g l−1), whose chemical compositions
also differ. Remarkably, PQQ-44 EPS contains large amounts of fucose, a sugar used in high-value
biotechnological applications. Furthermore, the genome of strain PQQ-42 contained a large nonribosomal
peptide synthase (NRPS) cluster with a previously unknown genetic structure. The synthesis
of enzymes and other bioactive compounds were also identified, indicating that PQQ-42 and PQQ-44
could have biotechnological applications.},
organization = {I.L. was supported by a Spanish Ministry of Economy, Industry and Competitiveness research project (AGL2015-
68806-R); Y.D. by an annual grant from the French National Scientific Research Center (CNRS); Y.D. and K.G.C.
by the French Embassy in Malaysia and K.G.C. by the University of Malaysia (grants H-50001-A000027 and
GA001-2016). The Institute for Integrative Biology of the Cell also received support from the LabEx Saclay
Plant Sciences-SPS (ANR-10-LABX-0040-SPS). M.T. was supported by an FPU Fellowship (FPU13-0466)
and the International Mobility Programme (EST15/00709) of the Spanish Ministry of Science and Education.
K.W.H. and T.M.C. received grants from the French Embassy in Malaysia. J.C.R. was supported by an FPU
Fellowship grant (FPU15-01717).},
publisher = {Springer Nature},
title = {Genomic analyses of two Alteromonas stellipolaris strains reveal traits with potential biotechnological applications},
doi = {10.1038/s41598-018-37720-2},
author = {Torres, Marta and Hong, Kar-Wai and Chong, Teik-Min and Reina, José Carlos and Chan, Kok-Gan and Dessaux and Dessaux, Yves and Llamas Company, Inmaculada},
}