@misc{10481/59445,
year = {2019},
url = {http://hdl.handle.net/10481/59445},
abstract = {Acanthamoeba spp. are the causative agents of a severe keratitis occurring mainly in contact lens
wearers. The genus comprises more than 24 species that are currently divided into 20 different genotypes (T1-T20)
according to sequence variations in the 18S rRNA gene. The objective of this study was to identify the genotypes
and sub-genotypes of Acanthamoeba isolates collected at the Parasitology Laboratory of the Public Health Institute
of Chile, the only laboratory in the country where Acanthamoeba screening is performed. This is the first report of
genotypic identification of clinical isolates of Acanthamoeba in Chile and one of the few in South America. T2, T4 and T11 genotypes were predominantly isolated from the Acanthamoeba keratitis patients in
Chile. Chilean predominant T4 sub-genotypes, which have also been reported worldwide, formed a separate cluster
of the minority T4 variants. This study provides useful information about the predominant genotypes and
subgenotypes that would be useful in selecting suitable strains to develop immunological and/or molecular
diagnostic assays in Chile.},
publisher = {Springer Nature},
keywords = {Acanthamoeba keratitis},
keywords = {T4 genotype},
keywords = {T11 genotype},
keywords = {T2 genotype},
keywords = {ASA.S1},
title = {Genotypic diversity of Acanthamoeba strains isolated from Chilean patients with Acanthamoeba keratitis},
doi = {10.1186/s13071-019-3302-5},
author = {Jercic, María Isabel and Osuna Carrillo De Albornoz, Antonio},
}