@misc{10481/59365,
year = {2019},
month = {12},
url = {http://hdl.handle.net/10481/59365},
abstract = {Breastfeeding is the ideal way to provide infants with the nutrients they need for healthy
growth and development. Milk composition changes throughout lactation, and fat is one of the
most variable nutrients in human milk. The aim of this study was to determine the main differences
between the fatty acid (FA) profile of human milk samples (colostrum, transitional, and mature
milk group) and infant formulas. Human milk samples were provided by lactating women from
Granada. Moreover, different commercial infant formulas were analyzed. FAs were determined using
gas chromatography coupled with mass spectrometry. According to the results, oleic acid was the
predominant monounsaturated fatty acid (41.93% in human milk and 43.53% in infant formulas),
while palmitic acid was the most representative saturated fatty acid (20.88% in human milk and
23.09% in infant formulas). Significant differences were found between human milk groups and infant
formulas, mainly in long-chain polyunsaturated FAs (LC-PUFAs). The content of araquidonic acid
(AA) and docoxahexaenoic acid (DHA) was higher in human milk (0.51% and 0.39%, respectively)
than in infant formulas (0.31% and 0.22%, respectively). Linoleic acid (LA) percentage (15.31%) in
infant formulas was similar to that found in human milk (14.6%). However, alpha-linolenic acid (ALA)
values were also much higher in infant formulas than in human milk (1.64% and 0.42%, respectively).},
organization = {This project was supported by the Spanish Ministry of Science, Innovation and Universities (Project
FIS-ISCIII PI17/02305) and the AGR-279 research group of the Department of Nutrition and Bromatology (University
of Granada).},
publisher = {MDPI},
keywords = {Fatty acids},
keywords = {Human milk},
keywords = {Infant formula},
keywords = {GC-MS/MS},
title = {A Comparison of Changes in the Fatty Acid Profile of Human Milk of Spanish Lactating Women during the First Month of Lactation Using Gas Chromatography-Mass Spectrometry. A Comparison with Infant Formulas},
doi = {10.3390/nu11123055},
author = {Sánchez Hernández, Silvia and Esteban Muñoz, Adelaida and Giménez Martínez, Rafael Jesús and Aguilar Cordero, María José and Miralles Buraglia, Beatriz and Olalla Herrera, Manuel},
}