@misc{10481/58545,
year = {2019},
month = {10},
url = {http://hdl.handle.net/10481/58545},
abstract = {The potential antiplatelet aggregation effects of mango pulp and its by-products (peel, husk
seed, and seed) due to the presence of bioactive compounds were explored. Among them, mango seed
exhibited a 72% percentage inhibition of platelet aggregation induced by adenosine 5’-diphosphate
(ADP) agonist with a demonstrated dose-dependent effect. This biological feature could be caused by
the chemical differences in phenolic composition. Mango seed was especially rich in monogalloyl
compounds, tetra- and penta-galloylglucose, ellagic acid, mangiferin, and benzophenones such
as maclurin derivatives and iriflophenone glucoside. Mangiferin showed an inhibitory effect of
31%, suggesting its key role as one of the main contributors to the antiplatelet activity of mango
seed. Therefore, mango seed could be postulated as a natural source of bioactive compounds with
antiplatelet properties to design functional foods or complementary therapeutic treatments.},
organization = {Ibero-American Program of Science and Technology for Development, Red iberoamericana de
aprovechamiento integral de alimentos autóctonos subutilizados (ALSUB-CYTED, 118RT0543). Financial support
of projects from program of aid for R + D + i of the Andalusian plan for research, development and innovation
(PAIDI 2020) of Junta de Andalucía and Junta de Comunidades de Castilla-La Mancha (SBPLY/17/180501/000509).},
publisher = {MDPI},
keywords = {Mango},
keywords = {By-products},
keywords = {Antiplatelet activity},
keywords = {Bioactive compounds},
keywords = {HPLC-DAD-q-TOF-MS},
title = {Antiplatelet Activity of Natural Bioactive Extracts from Mango (Mangifera Indica L.) and its By-Products},
doi = {10.3390/antiox8110517},
author = {Alañón, María Elena and Arráez Román, David and Segura Carretero, Antonio},
}