@misc{10481/58383,
year = {2017},
month = {2},
url = {http://hdl.handle.net/10481/58383},
abstract = {A specific HPLC (High-Performance Liquid Chromatography) method has been developed
and validated for the determination of vanillyl butyl ether in cosmetic products. The extraction
procedure with an isopropanol water 1:1 mixture is described. The method uses a RP-C-18 column
with isocratic elution and an ultraviolet (UV) detector. The mobile phase consists of a mixture of
acetonitrile and buffer (Na2HPO4 20 mM in water) (30:70 v/v) with a variable flow rate. The method
was validated with respect to accuracy, precision (repeatability and reproducibility), specificity and
linearity. The procedure described here is simple, selective and reliable for routine quality control
analysis and stability tests of commercially available cosmetic products.},
organization = {Francisco Ríos acknowledges the support fromthe Spanish Ministry of Economy, Industry and Competitiveness within the postdoctoral grant “Ayudas para contratos Torres Quevedo” (PTQ-15-07879).},
publisher = {MDPI},
keywords = {Vanillyl butyl ether},
keywords = {HPLC},
keywords = {Method validation},
keywords = {Cosmetic product},
title = {A Validated HPLC Method for the Determination of Vanillyl Butyl Ether in Cosmetic Preparations},
doi = {10.3390/cosmetics4010009},
author = {Ríos Ruiz, Francisco and Alberola, Antonio and Meléndez, Joaquín and Muedra, Gema and Trigo, Francisco},
}