@misc{10481/58293,
year = {2019},
url = {http://hdl.handle.net/10481/58293},
abstract = {Broiler chickens have an extreme physiology
(rapid growth rates) that challenges the correct
bone mineralization, being an interesting animal
model for studying the development of bone pathologies.
This work studies in detail how the mineralization,
chemistry, and structural organization of tibiae
bone in broiler chickens change with age during the
first 5 wk (37 D) from hatching until acquiring the final
weight for slaughter. During the early growth phase
(first 2 wk), the rapid addition of bone tissue does not
allow for bone organic matrix to fully mineralize and
mature, and seems to be a critical period for bone development
at which bone mineralization cannot keep
pace with the rapid growth of bones. The low degree
of bone mineralization and large porosity of cortical
bone at this period might be responsible of leg deformation
and/or other skeletal abnormalities commonly
observed in these birds. Later, cortical bone porosity
gradually decreases and the cortical bone became fully
mineralized (65%) at 37 D of age. At the same time,
bone mineral acquires the composition of mature bone
tissue (decreased amount of carbonate, higher crystallinity,
Ca/P = 1.68).},
publisher = {Oxford University Press},
keywords = {Broiler},
keywords = {Tibiae},
keywords = {Bone quality},
keywords = {Osteoporosis},
keywords = {Growth disorders},
title = {Changes with age (from 0 to 37 D) in tibiae bone mineralization, chemical composition and structural organization in broiler chickens},
doi = {10.3382/ps/pez363},
author = {Sánchez-Rodríguez, Estefania and Benavides Reyes, Cristina and Torres, Cibele and Domínguez Gasca, Nazaret and García Ruíz, Ana I. and González López, Santiago and Rodríguez Navarro, Alejandro},
}