@misc{10481/57770,
year = {2018},
url = {http://hdl.handle.net/10481/57770},
abstract = {Objective To investigate the relationship between seafood
consumption during pregnancy and the risk of delivering a
small for gestational age (SGA) newborn.
Design This case–control study included women with
SGA newborns and controls matched 1:1 for maternal age
(±2 years) and hospital.
Setting Five hospitals in Eastern Andalusia, Spain.
Participants 518 pairs of pregnant Spanish women. The
SGA group included women who delivered SGA newborns:
SGA was defined as a birth weight below the 10th
percentile of infants at a given gestational age. Controls
were women who delivered newborns with adequate birth
weights.
Interventions We collected data on demographic
characteristics, socioeconomic status, toxic habits and
diet. Midwives administered a 137-item Food Frequency
Questionnaire.
Outcome measures We calculated quintiles of seafood
intake and applied conditional logistic regression to
estimate ORs and 95% CIs.
Results Shellfish intake more than once/week yielded
a significant protective effect against an SGA newborn
(OR 0.25, 95% CI 0.08 to 0.76, after adjusting for energy,
educational level, smoking, prepregnancy body mass
index, weight and a history of preterm or low birthweight
newborn). The risk of an SGA newborn was lower among
women who consumed >29 g/day fish compared with
women who consumed ≤8 g (adjusted OR 0.63, 95% CI
0.41 to 0.98; p=0.025 for a trend). Similarly, the risk of an
SGA newborn was lower among women who consumed
>1 g/day of marine n-3 polyunsaturated fatty acids
compared with those who consumed ≤0.4 g/day (adjusted
OR 0.58, 95% CI 0.38 to 0.90; p=0.025 for a trend).
Conclusion An average seafood intake of at least 29 g/
day during pregnancy, equivalent to 2–3 servings/week,
reduced the risk of an SGA newborn, compared with an
average seafood intake of less than 8 g/day.},
organization = {The National Institute of Health Carlos III (PI11/02199) supported this
work.},
publisher = {BMJ},
title = {Maternal seafood intake and the risk of small for gestational age newborns: a case–control study in Spanish women},
doi = {10.1136/ bmjopen-2017-020424},
author = {Amezcua Prieto, María Del Carmen and Martínez Galiano, Juan Miguel and Salcedo Bellido, Inmaculada and Olmedo Requena, María Rocío and Bueno Cavanillas, Aurora and Delgado Rodríguez, Miguel},
}