@misc{10481/57590,
year = {2018},
month = {11},
url = {http://hdl.handle.net/10481/57590},
abstract = {Cold induced thermogenesis (CIT) in humans results mainly from the combination
of both brown adipose tissue (BAT) and skeletal muscle thermogenic activity. The
relative contribution of both tissues to CIT and to cold induced nutrient oxidation
rates (CI-NUTox) remains, however, to be elucidated. We investigated the association
of BAT and skeletal muscle activity after a personalized cold exposure with CIT
and CI-NUTox in 57 healthy adults (23.0   2.4 years old; 25.1   4.6 kg/m2; 35
women). BAT and skeletal muscle (paracervical, sternocleidomastoid, scalene, longus
colli, trapezius, parathoracic, supraspinatus, subscapular, deltoid, pectoralis major, and
triceps brachii) metabolic activity were assessed by means of a 18Fluorodeoxyglucose
positron emission tomography-computed tomography scan preceded by a personalized
cold exposure. The cold exposure consisted in remaining in a mild cold room for 2 h at
19.5–20 C wearing a water perfused cooling vest set at 3.8 C above the individual
shivering threshold. On a separate day, we estimated CIT and CI-NUTox by indirect
calorimetry under fasting conditions for 1 h of personalized cold exposure. There was
no association of BAT volume or activity with CIT or CI-NUTox (all P > 0.2).},
organization = {The study was supported by the Spanish Ministry of Economy
and Competitiveness (PTA 12264-I), Fondo de Investigación
Sanitaria del Instituto de Salud Carlos III (PI13/01393), and
Retos de la Sociedad (DEP2016-79512-R), Fondos Estructurales},
publisher = {Frontiers Media},
keywords = {Brown fat},
keywords = {Non-shivering thermogenesis},
keywords = {Energy expenditure},
keywords = {Energy balance},
keywords = {Obesity},
title = {Brown Adipose Tissue and Skeletal Muscle 18F-FDG Activity After a Personalized Cold Exposure Is Not Associated With Cold-Induced Thermogenesis and Nutrient Oxidation Rates in Young Healthy Adults},
doi = {10.3389/fphys.2018.01577},
author = {Sánchez-Delgado, Guillermo and Martínez Téllez, Borja Manuel and García Rivero, Yolanda and Acosta Manzano, Francisco Miguel and Amaro Gahete, Francisco José and Alcantara, Juan M.A. and Llamas Elvira, José Manuel and Ruiz Ruiz, Jonatan},
}