@misc{10481/55770,
year = {2019},
month = {4},
url = {http://hdl.handle.net/10481/55770},
abstract = {The aim of the study was to evaluate sleep duration and sleep variability in relation to
serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis
of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndrome
in the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep
duration and sleep variability were measured. Linear regression models were fitted to examine the
aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated
with SUA concentrations (  β= -0.07, p = 0.047). Further adjustment for leukocytes attenuated this
association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA
to creatinine ratio ( β= -0.15, p = 0.001). The findings of this study suggest that longer sleep duration
is associated with lower SUA concentrations and lower SUA to creatinine ratio.},
organization = {The PREDIMED-Plus trial was supported by the official funding agency for biomedical research of
the Spanish government, ISCIII, through the Fondo de Investigación para la Salud (FIS), which is co-funded
by the European Regional Development Fund (three coordinated FIS projects led by Jordi Salas-Salvadó and
Josep Vidal, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462,
PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696,
PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501,
PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347,
PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926), the Especial
Action Project entitled: Implementación y evaluación de una intervención intensives obre la actividad física
Cohorte PREDIMED-PLUS grant to Jordi Salas-Salvadó, the European Research Council (Advanced Research
Grant 2013–2018; 340918) grant to Miguel Ángel Martínez-Gonzalez, the Recercaixa grant to Jordi Salas-Salvadó (2013ACUP00194), the grant from the Consejería de Salud de la Junta de Andalucía (PI0458/2013; PS0358/2016),
grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013; PS0358/2016; PI0137/2018), the
PROMETEO/2017/017 grant from the Generalitat Valenciana, the SEMERGEN grant, and FEDER funds (CB06/03).
Olga Castaner was granted by the JR17/00022, ISCIII. Christopher Papandreou is supported by a postdoctoral
fellowship granted by the Autonomous Government of Catalonia (PERIS 2016–2020 Incorporació de Científics
I Tecnòlegs, SLT002/0016/00428). José C. Fernández-García is supported by a research contract from Servicio
Andaluz de Salud (SAS) (B-0003-2017). None of the funding sources took part in the design, collection, analysis, or
interpretation of the data, or in the decision to submit the manuscript for publication. The corresponding authors
had full access to all the data in the study and had final responsibility forsubmitting for publication.},
publisher = {MDPI},
keywords = {Sleep duration},
keywords = {Actigraphy},
keywords = {Serum uric acid},
keywords = {Serum uric acid to creatinine ratio},
title = {Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk},
author = {Papandreou, Cristopher and Bueno Cavanillas, Aurora},
}