@misc{10481/54850,
year = {2019},
month = {2},
url = {http://hdl.handle.net/10481/54850},
abstract = {Aim: The aim of this study was to examine the clinical and histological differences of
using a combination of alloplastic beta triphasic calcium phosphate (_ β-TCP) and a cross-linked
collagen membrane versus autologous platelet-rich fibrin (PRF-L) in ridge preservation after dental
extraction. Material and methods: Fifty-one patients were included in this observational case-series
study. Dental extractions were performed, after which 25 patients were grafted with _-TCP and
26 with PRF-L. After four months of healing, clinical, radiological, histomorphometric and histological
evaluations were performed. Results: A significantly higher percentage of mineralized tissue was
observed in samples from the PRF-L grafted areas. Cellularity was higher in PRF-L grafted areas
(osteocytes in newly formed bone per mm2 = 123.25 (5.12) vs. 84.02 (26.53) for PRF-L and β-TCP,
respectively, p = 0.01). However, sockets grafted with PRF-L showed a higher reduction in the
bucco-lingual dimension after four months of healing (2.19 (0.80) vs. 1.16 (0.55) mm, p < 0.001), as well
as a higher alteration in the final position of the mid muco-gingival junction (1.73 (1.34) vs. 0.88 (0.88)
mm, p < 0.01). Conclusion: PRF-L concentrate accelerates wound healing in post-extraction sockets
in terms of new mineralized tissue component. However, the use of  β-TCP biomaterial appears to be
superior to maintain bucco-lingual volume and the final position of the muco-gingival junction.},
organization = {The authors of this manuscript were partially supported by Research Groups #CTS-138
(FO) and #CTS-1028 (PGM, MPM) (Junta de Andalucía, Spain). Grafting materials were generously provided by
Dentium Co., Ltd., Seoul, Korea.},
publisher = {MDPI},
keywords = {Beta triphasic calcium phosphate (  β -TCP)},
keywords = {Platelet-rich fibrin (PRF-L)},
keywords = {Ridge augmentation},
keywords = {Post-extraction socket},
title = {Composite Alloplastic Biomaterial vs. Autologous Platelet-Rich Fibrin in Ridge Preservation},
doi = {10.3390/jcm8020223},
author = {Mendoza-Azpur, Gerardo and Olaechea, Allinson and Padial Molina, Miguel and O'Valle Ravassa, Francisco Javier and Mesa Aguado, Francisco Luis and Galindo Moreno, Pablo Antonio},
}