@misc{10481/52423,
year = {2010},
month = {12},
url = {http://hdl.handle.net/10481/52423},
abstract = {Introducción: Diferentes técnicas quirúrgicas se han utilizado para la reconstrucción uretral, entre ellas la
utilización de injertos de mucosa oral. El objetivo del trabajo es estudiar las modificaciones estructurales y
ultraestructurales en los tejidos injertados sometidos a condiciones ambientales diferentes a las del tejido original.
Material y métodos: 20 ratas Wistar macho de 300 g sometidas a anestesia general. Al grupo control se seccionó
longitudinalmente la uretra peneana suturándola posteriormente. Grupos estudio, se realizó uretroplastia con
injertos de mucosa oral autóloga y análisis (fijación con formaldehido y tinción H&E) tras sacrificio a los 7, 14 y 30
días.
Resultados: La técnica empleada fue factible. El análisis de los tejidos orales implantados mostró adecuada
integración, que fue completa a los 30 días presentando 5-6 capas de células planas estructura semejante al
epitelio uretral.
Conclusiones: La mucosa oral como injerto heterotópico se diferencia de forma adecuada generando un tejido
estructuralmente similar a la uretra nativa.},
abstract = {Introduction: Several surgical techniques have been used for urethral reconstruction. In this context, oral
mucosa grafts are currently required. The aim of this study was to analyze the structural and ultraestructural
modifications of grafted tissues exposed to different environmental conditions.
Material and methods: 20 male Wistar rats under general anesthesia were used. Control group was set, and
groups of study were set, and underwent an urethroplasty with oral mucosa graft analyzed at 7, 14 and 30
days.
Results: The technique used was feasible. The analysis in oral grafted tissues showed an adequate
integration level, with a shrinking interphase formation between the oral and urethral mucosa. At 30 days,
the integration was completed and the oral mucosa showed 5-6 flat cell layers, with a similar structure to the
urethral epithelium.
Conclusions: The oral mucosa used as heterologous graft was able to differentiate in an adequate way to
generate a structurally similar tissue to the native urethra.},
organization = {Financiado por: FIS expediente P 1070619},
publisher = {Real Academia de Medicina y Cirugía de Andalucía Oriental; Universidad de Granada},
keywords = {Uretroplastia},
keywords = {Injerto mucosa oral},
keywords = {Cirugía experimental},
keywords = {Análisis histológico},
keywords = {Rata},
keywords = {Urethroplasty},
keywords = {Oral mucosa graft},
keywords = {Experimental surgery},
keywords = {Histological analysis},
keywords = {Rat},
title = {Caracterización histológica en uretroplastias experimentales de mucosa oral},
author = {Martín Cano, Fátima and Marañés Gálvez, C. and Liceras Liceras, Esther and García Gómez, M. and Díaz Moreno, E. and Ruiz Montes, A.M. and Garzón Bello, Ingrid Johanna and Fernández Valadés, Ricardo},
}