@misc{10481/47518,
year = {2015},
month = {8},
url = {http://hdl.handle.net/10481/47518},
abstract = {A microfluidic chip for cross-linked enzyme crystals (McCLEC) is presented and demonstrated to be a stable, reusable and robust biocatalyst-based device with very promising biotechnological applications. The cost-effective microfluidic platform allows in situ crystallization, cross-linking and enzymatic reaction assays on a single device. A large number of enzymatic reuses of the McCLEC platform were achieved and a comparative analysis is shown illustrating the efficiency of the process and its storage stability for more than one year.},
organization = {This work has been partly funded by the MICINN (Spain) projects BIO2010-16800 (JAG) and BIO2012-34937 (SMR), the European Commission (Contract No. 317916) under the LiPhos project (AL and IRR), “Factoría Española de Cristalización” Consolider-Ingenio 2010 (JAG and MCM) and EDRF Funds (JAG and AL). MCM thanks the Consejo Superior de Investigaciones Científicas (CSIC, Spain) for a JAE predoc fellowship.},
publisher = {Royal Society of Chemistry},
keywords = {Microfluidic},
keywords = {Crystallization},
keywords = {Device},
keywords = {McCLEC},
keywords = {Enzyme Assay},
title = {McCLEC, a robust and stable enzymatic based microreactor platform},
doi = {10.1039/c5lc00776c},
author = {Conejero-Muriel, Mayte and Rodríguez-Ruiz, Isaac and Martínez-Ruiz, Sergio and Llobera, Andreu and Gavira Gallardo, José Antonio},
}