@misc{10481/35709,
year = {2015},
url = {http://hdl.handle.net/10481/35709},
abstract = {In the present study we have performed both a meta-analysis and an analytical study exploring the presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii antibodies in a sample of 143 schizophrenic patients and 143 control subjects. The meta-analysis was performed on papers published up to April 2014. The presence of serum immunoglobulin G and immunoglobulin A was performed by enzyme-linked immunosorbent assay test. The detection of microbial DNA in total peripheral blood was performed by nested polymerase chain reaction. The meta-analysis showed that: 1) C. pneumoniae DNA in blood and brain are more common in schizophrenic patients; 2) there is association with parasitism by T. gondii, despite the existence of publication bias; and 3) herpes viruses were not more common in schizophrenic patients. In our sample only anti-Toxoplasma immunoglobulin G was more prevalent and may be a risk factor related to schizophrenia, with potential value for prevention.},
organization = {Part of this work was presented at the Royal Academy of Medicine of Spain.},
publisher = {Dove Press},
keywords = {Meta-analysis},
keywords = {Analytical study},
keywords = {Chlamydia pneumoniae},
keywords = {Herpes simplex virus type 1},
keywords = {Human herpes virus 6},
keywords = {Toxoplasma gondii},
keywords = {Schizophrenia},
title = {Different presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii in schizophrenia: meta-analysis and analytical study},
doi = {10.2147/NDT.S79285},
author = {Gutiérrez-Fernández, José and Luna Del Castillo, Juan De Dios and Mañanes-González, Sara and Carrillo-Ávila, José Antonio and Gutiérrez, Blanca and Cervilla, Jorge A. and Sorlozano Puerto, Antonio},
}