@misc{10481/32398,
year = {2010},
url = {http://hdl.handle.net/10481/32398},
abstract = {[Background]

Old age is associated with an involuntary and progressive but physiological loss of muscle mass. The aim of this study was to evaluate the effects of exclusive consumption for 6 months of a protein-enriched enteral diet with a relatively high content of branched-chain amino acids on albuminemia, cortisolemia, plasma amino acids, insulin resistance, and inflammation biomarkers in elderly patients.
[Methods]

Thirty-two patients from the Clinical Nutrition Outpatient Unit at our hospital exclusively consumed a protein-enriched enteral diet for 6 months. Data were collected at baseline and at 3 and 6 months on anthropometric and biochemical parameters and on plasma concentrations of amino acids, cortisol, adrenocorticotropic hormone, urea, creatinine, insulin resistance, and inflammation biomarkers.
[Results]

The percentage of patients with albumin concentration below normal cut-off values decreased from 18% to 0% by the end of the study. At 6 months, concentrations of total plasma (p = 0.008) and essential amino acids (p = 0.011), especially branched-chain amino acids (p = 0.031), were higher versus baseline values, whereas 3-methylhistidine (p = 0.001), cortisol (p = 0.001) and adrenocorticotropic hormone (p = 0.004) levels were lower.
[Conclusions]

Regular intake of specific protein-enriched enteral formula increases plasma essential amino acids, especially branched-chain amino acids, and decreases cortisol and 3-methylhistidine, while plasma urea and creatinine remain unchanged.},
organization = {This study was financed by Vegenat S.A. Vegenat S.A. has designed the new formula for EN.},
publisher = {Biomed Central},
keywords = {Muscle mass},
keywords = {Performance},
keywords = {Ingestion},
keywords = {Men},
keywords = {Strength},
keywords = {Hormones},
keywords = {Humans},
keywords = {Women},
keywords = {Age},
title = {A specific protein-enriched enteral formula decreases cortisolemia and improves plasma albumin and amino acid concentrations in elderly patients},
doi = {10.1186/1743-7075-7-58},
author = {Olza Meneses, Josune and Mesa García, María Dolores and Poyatos Martínez, Rafael Miguel and Aguilera García, Concepción María and Moreno-Torres, Rosario and Pérez, Milagros and Pérez De La Cruz, Antonio Jesús and Gil Hernández, Ángel},
}