@misc{10481/112459, year = {2026}, month = {3}, url = {https://hdl.handle.net/10481/112459}, abstract = {The natural product composition of the hexane and methyl tert-butyl ether extracts of Dittrichia viscosa roots was examined. Eight terpenoids were identified by nuclear magnetic resonance (NMR) and high resolution mass spectroscometry (HRMS) techniques, four of which (1, 5, 6 and 8) are reported here for the first time as natural products. Of these eight compounds, four are thymol derivatives (1–4), two are guaianolides (5 and 7) and two are himachalanes (6 and 8). Additionally, the occurrence of himachalanes in this species is reported for the first time. Furthermore, a study of the potential plant protection effects of some of these natural products and the chemical derivative 6a was carried out. Promising preliminary results were obtained for compounds 1–3 and 6a as antifeedant agents against Spodoptera littoralis; 1–3 and 5 against Myzus persicae; 1–3 against Rhopalosiphum padi; and 4 as nematicide against Meloidogyne javanica. Finally, the phytotoxic activity of compounds 4, 5 and 6a against the monocotyledonous species Lolium perenne was also proven.}, organization = {State Research Agency, 10.13039/501100011033 and Unidad Asociada UGR-CSIC BIOPLAG - (PID2024-156361OB-C22)}, publisher = {MDPI}, keywords = {Dittrichia viscosa roots}, keywords = {Terpenes}, keywords = {Sesquiterpene lactones}, title = {Isolation and Characterization of Terpenoids with Promising Biopesticide Activity from Dittrichia viscosa (L.) Roots}, doi = {10.3390/ijms27072949}, author = {Segura Navarro, María José and Quílez Del Moral, José Francisco and Galisteo, Alberto and López Pérez, José Luis and Molina Inzunza, Diego O. and Andrés, María Fe de and González Coloma, Azucena and Fernández Barrero, Alejandro}, }