@misc{10481/111637,
year = {2016},
month = {10},
url = {https://hdl.handle.net/10481/111637},
abstract = {Medicago sativa L. (alfalfa) is a leguminous plant with beneficial effects on altered glucose
and lipid metabolism, moreover exhibiting hypotensive activity. We improved the functional
properties of alfalfa, growing the plant under specific soil conditions of high salinity.
We determined the main bioactive compounds and five new phenolic compounds were identified.
Alfalfa grown under high salinity conditions was added to experimental diets and
assayed in an experimental model of spontaneously hypertensive rat. Among the main findings,
a slight decrease on blood pressure, a reduction in the risk of kidney stone formation,
a protective action against oxidative damage in fatty liver disease, as well as an improvement
of glucose metabolism through the normalization of the gcg expression in colon should
be underlined. Alfalfa can be used as an efficient functional food for the dietary prevention
and treatment of several metabolic alterations, characteristic of the metabolic syndrome},
organization = {Grants P07-AGR-2704 and P09AGR-
4658 from Junta de Andalucía, Spain},
organization = {Ministry of Economy and Competitiveness
(MINECO, Spain), the European Union and FEDER program
through project n° AGL2013-43247-R},
publisher = {Elsevier},
keywords = {Alfalfa},
keywords = {Blood pressure},
keywords = {Polyphenols},
keywords = {Glucagon-like peptide-1},
keywords = {Spontaneously hypertensive rat},
title = {Medicago sativa L., a functional food to relieve hypertension and metabolic disorders in a spontaneously hypertensive rat model},
doi = {https://doi.org/10.1016/j.jff.2016.08.013.},
author = {Martínez Martínez, Rosario and Kapravelou, Garyfallia and Porres Foulquie, Jesús María and Cantarero Malagón, Antonio Samuel and Aranda Ramírez, Pilar and López-Jurado Romero De La Cruz, María},
}