@misc{10481/111581, year = {2021}, month = {12}, url = {https://hdl.handle.net/10481/111581}, abstract = {Background: We previously demonstrated that a hand hygiene program, including hand sanitizer and educational measures, for day care center (DCC) staff, children, and parents was more effective than a soap-and-water program, with initial observation, in preventing respiratory infections (RIs) in children attending DCCs. We analyzed the cost-effectiveness of these programs in preventing RIs. Methods: A cluster, randomized, controlled and open study of 911 children aged 0 to 3 years, attending 24 DCCs in Almeria. Two intervention groups of DCC-families performed educational measures and hand hygiene, one with soap-and-water (SWG) and another with hand sanitizer (HSG). The control group (CG) followed usual hand-washing procedures. RI episodes, including symptoms, treatments, medical contacts, complementary analyses, and DCC absenteeism days, were reported by parents. A Bayesian cost-effectiveness model was developed. Results: There were 5201 RI episodes registered. The adjusted mean societal costs of RIs per child per study period were CG: €522.25 (95% confidence interval [CI]: 437.10 to 622.46); HSG: €374.53 (95% CI: 314.90 to 443.07); SWG: €494.51 (95% CI: 419.21 to 585.27). The indirect costs constituted between 35.7% to 43.6% of the total costs. Children belonging to the HSG had an average of 1.39 fewer RI episodes than the CG and 0.93 less than the SWG. It represents a saving of societal cost mean per child per study period of €147.72 and €119.15, respectively. The HSG intervention was dominant versus SWG and CG. Conclusions: Hand hygiene programs that include hand sanitizer and educational measures for DCC staff, children, and parents are more effective and cost less than a program with soap and water and initial observation in children attending DCCs.}, publisher = {AAP Publications}, keywords = {Child care}, keywords = {Infectious Diseases}, keywords = {Medical education}, title = {Child Care Center Hand Hygiene Programs' Cost-Effectiveness in Preventing Respiratory Infections}, doi = {10.1542/peds.2021-052496}, author = {Azor-Martinez, Ernestina and García Mochón, Leticia and López Lacort, Mónica and Marie Strizzi, Jenna and Muñoz Vico, Francisco Javier and Jiménez-Lorente, Carmen Pilar and Fernández-Campos, María Amparo and Bueno Rebollo, Cristina and del Castillo-Aguas, Guadalupe and Balaguer-Martinez, Josep Vicent and Gimenez-Sanchez, Francisco}, }