@misc{10481/110860, year = {2026}, month = {6}, url = {https://hdl.handle.net/10481/110860}, abstract = {Luminescent lanthanide (Ln3+) complexes are highly attractive for diverse applications, particularly as luminescent probes, owing to their exceptional photophysical properties, including long-lived photoluminescence, narrow-band emissions, and large Stokes shifts. These characteristics enable advanced techniques like time-gated detection, significantly enhancing signal-to-noise ratios in biological samples. Traditional luminescent Ln3+ complexes are characterized by bulky organic cryptands and/or conjugated chromophoric antennae for prompting the metal excitation prior to emission. This strategy is usually synthetically demanding, including complexation reactions that last for several days. To overcome this limitation, self-assembly strategies in solution have recently emerged as a powerful approach. This review discusses recent advancements in self-assembled luminescent Ln3+ complexes across various solvents, with particular emphasis on their behavior and performance in aqueous environments. It highlights the growing importance of water-compatible self-assembled luminescent Ln3+ complexes for biological applications, underscoring their potential in cell imaging and biosensing. By addressing key design challenges and showcasing diverse functionalities, this review provides a comprehensive and accessible overview for researchers in chemistry, biochemistry, and biology interested in the rapidly evolving field of lanthanide luminescence.}, organization = {AEI /10.13039/501100011033 and by ERDF, EU - (PID2023-148243OB-I00)}, organization = {AEI/10.13039/501100011033 - (PID2020-114256RB-I00)}, organization = {Conserjería de Universidad, Investigación e Innovación (Junta de Andalucía) - (P21_00212)}, organization = {FEDER/Junta de Andalucía-Conserjería de Transformación Económica, Industria, Conocimiento y Universidades - (A-FQM-386-UGR20)}, publisher = {Elsevier}, keywords = {Lanthanide}, keywords = {Antenna}, keywords = {Self-assembling}, title = {Self-assembled luminescent lanthanide complexes in solution as rising stars for sensing and bioimaging}, doi = {10.1016/j.ccr.2026.217676}, author = {Ruiz Arias, Álvaro and Fueyo-Gonzalez, Francisco and Orte Gutiérrez, Ángel and González Vera, Juan Antonio}, }