@misc{10481/110824,
year = {2022},
month = {11},
url = {https://hdl.handle.net/10481/110824},
abstract = {The present study was undertaken to evaluate the occupational exposure to PAHs of long-term workers in a specific petroleum refinery in Albania. The main route of exposure to these pollutants is via inhalation within a highly contaminated work environment. Serum samples from workers were collected and analyzed. A cloud-point extraction method was applied to isolate and concentrate PAHs from samples using Triton X-100 as the extraction agent. The phase separation of micellar serum solutions was induced with the addition of sodium chloride. The analyses were performed by gas chromatography/mass spectrometry using a capillary column HP-5MS. The PAHs analyzed were acenaphthene, acenaphthylene, anthracene, benzo[α]anthracene, benzo[α]pyrene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[g,h,i]perylen, chrysene, dibenzo[α,h]anthracene, fluorene, indeno[1,2,3-cd]pyrene, naphthalene, phenanthrene and pyrene. Mean concentration of analytes ranged from 4 ng mL-1 for fluorene and anthracene to 110 ng mL-1 for dibenzo[α,h]anthracene. The compositional profile of the PAHs was primarily 4-6 rings PAHs. Diagnostic isomeric ratios of benzo[α]anthracene/(benzo[α]anthracene + chrysene) and phenanthrene/anthracene suggest that the PAHs in the serum were primarily pyrogenic PAHs. The bioaccumulation trend of the PAHs in the workers proved conditional to their physical location within the workplace.},
organization = {Spanish Government (FEDER-ISCIII PI20/01278)},
organization = {FEDER/Regional Government of Andalusia - Ministry of Economy and Knowledge (B.RNM.362.UGR20 and PE-0250-2019)},
organization = {FEDER Andalusia (2014–2020)},
publisher = {Elsevier},
keywords = {Gas chromatography-mass spectrometry},
keywords = {PAHs},
keywords = {Cloud-point extraction},
title = {Analysis of polycyclic-aromatic hydrocarbons in blood serum samples obtained from oil refinery workers. Determination of occupational exposure},
doi = {10.1016/j.apr.2022.101589},
author = {Çipa, Morsina and Gómez Regalado, María del Carmen and Navalón, Alberto and Marku, Elda and Zafra-Gomez, Alberto},
}