@misc{10481/110215,
year = {2022},
url = {https://hdl.handle.net/10481/110215},
abstract = {Traditionally, edible flowers have been used as foods and for therapeutic purposes, today they have gained importance due to their bioactive compounds such as flavonols, anthocyanins or other phenolic compounds, which give them potential for biomedical applications. This work evaluated a methanolic extract of Tulbaghia violacea. Eleven individual phenolic compounds were found and quantified by mass spectrometry in the extract. Antioxidant activity tests (TEAC, FRAP and DPPH) and other characterization parameters were assayed (total phenolic content and total flavonoid content). In vitro studies showed antitumoral activity against ovarian tumoral cells mediated by the induction of non-dependent caspase cell death and by the activation of reactive oxygen species. The effect of the extract against features of Alzheimer disease was in vivo assayed in Caenorhabditis elegans. Tulbaghia extract led to a reduction in the 1–42 beta amyloid peptide formation and prevented oxidative stress. These results suggested that Tulbaghia violacea could be a new source of phenolic compounds for nutraceuticals and functional food development.},
organization = {FEDER/Junta de Andalucía-Consejería de Economía y Conocimiento
Grant BAGR-193-UGR18, B-AGR-652-UGR20 and P20_00336.},
title = {Unravelling potential biomedical applications of the edible flower Tulbaghia violacea},
doi = {https://doi.org/10.1016/j.foodchem.2022.132096},
author = {Rivas García, Lorenzo and Romero Márquez, José Manuel and Navarro Hortal, María Dolores and Esteban Muñoz, Adelaida and Giampieri, Francesca and Sumalla Cano, Sandra and Battino, Maurizio and Quiles Morales, José Luis and Llopis González, Juan and Sánchez González, Cristina},
}