@misc{10481/110203,
year = {2022},
url = {https://hdl.handle.net/10481/110203},
abstract = {The aim of this study was to investigate the association between dietary sodium, potassium, and sodium:potassium
ratio and clinical disease activity parameters, damage accrual, and cardiovascular disease risk factors in a population of patients
with systemic lupus erythematous (SLE). A cross-sectional study including a total of 280
patients was conducted (90.4% females; mean age 46.9 ± 12.85 years). Data collection: The SLE Disease Activity Index
(SLEDAI-2K) and the SDI Damage Index were used to assess disease activity and disease-related damage, respectively. A 24-
hour diet recall was used to estimate dietary intake of sodium and potassium. Dietary sodium intake was significantly
associated with anti-dsDNA (β =  .005; 95% CI [.002 .008]; p = .001) and complement C4 level (β =  .002; 95% CI [ .003,
.000]; p = .039). Dietary potassium intake was also significantly associated with complement C3 level (β =  .004; 95% CI
[ .007,  .001]; p = .021). Multiple logistic regression models revealed a positive association between dietary sodium intake and
the risk of having hsCRP > 3 (p = .005) and an inverse association between dietary potassium intake and the risk of having
hsCRP > 3 (p = .004). SLE patients with higher dietary sodium and lower dietary potassium intakes had an
increased risk of higher hsCRP. Dietary sodium intake was significantly associated with anti-dsDNA and complement C4 level,
while dietary potassium intake was associated with complement C3 level, supporting that dietary sodium and potassium intakes
might play a key role in markers related to disease activity in SLE patients.},
publisher = {Sage},
keywords = {Systemic Lupus Erithematosus},
keywords = {Sodium Intake},
keywords = {Potasium intake},
keywords = {sodium: potassium ratio},
title = {Dietary Sodium, Potassium, and Sodium to Potassium Ratio in Patients With Systemic Lupus Erythematosus},
doi = {10.1177/10998004211065491},
author = {Correa Rodríguez, María and Del Olmo Romero, Sara and Pocovi Gerardino, Gabriela and Callejas Rubio, José Luis and Ríos Fernández, Raquel and Ortego Centeno, Norberto and Rueda Medina, Blanca María},
}