@misc{10481/109978,
year = {2025},
month = {12},
url = {https://hdl.handle.net/10481/109978},
abstract = {Background: Childhood is a life stage particularly sensitive to malnutrition, including obesity, celiac disease, and food allergies. Zn is an essential element in development, metabolism, and the regulation of  inflammatory processes and oxidative stress.Objective: Zn bioaccessibility (Zn-BA), an indicator of  the fraction of  Zn available for intestinal absorption, is commonly evaluated through in vitro digestion models. This study applied a novel in vitro digestion–fermenta-tion method to assess Zn-BA in various raw and cooked foods using fecal inocula from children with gluten-re-lated disorders (GRD-CH), obesity (OB-CH), and allergy/intolerance to cow’s milk protein (AICM-CH).Results: The results showed that Zn bioaccessibility in the large intestine (Zn-BALI) values were significantly lower in these clinical groups compared to healthy children (P < 0.001). Mean Zn-BALI values in the large intestine of  all foods in GRD-CH are significantly higher (34.7 ± 28.8%) than those determined in OB-CH (29.6 ± 30.1%) and AICM-CH (26.7 ± 30.4%) (P < 0.001). For allergic children, Zn-BALI in animal foods was significantly lower than in plant foods and in both plant and animal foods in the other children’s groups (P  <  0.05).  Zn-BALI  in  animal  foods  cooked  in  liquid  media  (frying/boiling)  was  significantly  higher  than  when cooked with hot air (roasting/grilling).Conclusion:  In  children,  the  studied  diseases  diminished  the  Zn-BALI,  which  could  negatively  affect  their  appropriate long-term development. In sick children, the higher Zn-BALI in celiac children is probably related to differences in gut microbiota composition, as well as to different metabolites and ligands obtained by the fermentation processes, a fact that should be addressed in future studies.},
organization = {AGR-295-ALIMENTACIÓN Y MICROBIOTA INTESTINAL: RELACIÓN CON LOS ALIMENTOS Y SU PROCESADO (FOODMICROGUT) (DPTO DE NUTRICIÓN Y BROMATOLOGÍA)},
publisher = {SNF Swedish Nutrition Foundation},
title = {Zinc bioaccessibility of foodstuffs after in vitro study in children with illnesses},
doi = {http://dx.doi.org/10.29219/fnr.v69.11032},
author = {García-Conde, Úrsula and Navarro-Moreno, Miguel and Navajas Porras, Beatriz and Hinojosa-Nogueras, Daniel and Delgado-Osorio, Adriana and Pérez Burillo, Sergio and Navarro Alarcón, Miguel and Pastoriza de la Cueva, Silvia and Douros, Kostantinos and Rufián Henares, José Ángel},
}