@misc{10481/109760,
year = {2013},
month = {2},
url = {https://hdl.handle.net/10481/109760},
abstract = {Ras GTPases are important regulators of pathways controlling proliferation, differentiation and transformation. Three ubiquitously expressed almost identical Ras genes are not functionally redundant; this has been attributed to their distinctive trafficking and localization profiles. A palmitoylation cycle controls the correct compartmentalization of H-Ras and N-Ras. We review recent data that reveal how this cycle can be regulated by membrane organization to influence the spatiotemporal signalling of Ras.},
organization = {Royal Society},
organization = {North West Cancer Research Fund},
organization = {Wellcome Trust},
organization = {DGF-DIP [KL 1948/1-1, GA 309/10-1]},
organization = {Ministry of Science & Technology, Israel},
publisher = {Portland Press},
keywords = {Compartmentization},
keywords = {Nanocluster},
keywords = {Palmitoylation},
keywords = {RAS},
title = {The role of palmitoylation in regulating Ras localization and function},
doi = {10.1042/BST20120268},
author = {Eisenberg, Sharon and Laude, Alex J. and Beckett, Alison J. and Mageean, Craig J. and Aran, Verónica and Hernández Valladares, María del Carmen and Henis, Yoav I. and Prior, Ian A.},
}