@misc{10481/108723,
year = {2025},
month = {11},
url = {https://hdl.handle.net/10481/108723},
abstract = {Introduction: Cardiac resynchronization therapy (CRT) is a well‐established treatment for patients with heart failure (HF).
Recently, left bundle branch area pacing (LBBAP) has emerged as a more physiological alternative to biventricular pacing (BVP)
for CRT. This study aimed to evaluate the cost‐utility of LBBAP CRT compared with BVP CRT.
Methods: A cost‐utility, non‐randomized, prospective, multicenter, quasi‐experimental study was performed in four
referral centers. Patients eligible for CRT were treated with LBBAP or BVP, depending on the participating center. The
primary health outcome was quality‐adjusted life years (QALYs) measured using the EQ‐5D‐5L questionnaire, and the
analysis considered the cost of the implant and all procedure‐related events over the 12‐month follow‐up. Clinical outcomes were also evaluated.
Results: Sixty‐two consecutive patients were included (42 LBBAP CRT and 20 BVP CRT). Clinical outcomes were similar in
both groups. The incremental cost‐utility analysis showed that LBBAP CRT generated an average cost saving of €2391.02 per
patient compared with BVP (95% CI −330.28 to 5112.69), while providing an incremental gain of 0.07 QALYs (95% CI −0.03
to 0.16).
Conclusions: LBBAP CRT could be an efficient alternative to BVP CRT for cardiac resynchronization with similar clinical and
QALY outcomes but potentially significant average cost savings per patient.},
publisher = {John Wiley & Sons, Ltd.},
keywords = {biventricular pacing},
keywords = {cardiac resynchronization therapy},
keywords = {cost‐utility},
title = {Cost‐Utility Analysis of Left Bundle Branch Area Versus Biventricular Pacing for Cardiac Resynchronization Therapy: A Multicenter, Prospective, Quasi‐Experimental Study},
doi = {10.1111/jce.70202},
author = {Sánchez‐Moreno, José M. and García Mochón, Leticia and Molina Lerma, Manuel and Gutiérrez‐Ballesteros, Guillermo and Frutos‐López, Manuel and Pavón‐Jiménez, Ricardo and Olvera-Porcel, María del Carmen and Jiménez-Jáimez, Juan and Álvarez, Miguel},
}