@misc{10481/108495,
year = {2025},
month = {11},
url = {https://hdl.handle.net/10481/108495},
abstract = {Objective: This study aimed to determine the association between periodontal disease
and dementia in older adults in Lima Centro. Materials and methods: A cross-sectional
analytical study was conducted in 112 institutionalized older adults, who were clinically
evaluated using the Periodontal Screening and Recording (PSR) system. Bivariate analyses
were performed using the chi-square test, Mann–Whitney U test, and Student’s t-test.
Logistic regression was used to estimate the crude and adjusted odds ratios with 95%
confidence intervals, with p < 0.05 considered statistically significant. Results: The results
showed that 49.11% of the participants scored a code 3 in the PSR system, indicating
periodontal pockets of 3 to 5 mm, bleeding, and bacterial plaque, while 79.46% exhibited
the presence of bacterial plaque. Likewise, older adults with dementia were observed to
have clinical plaque upon probing, whereas 40.35% of older adults without a dementia
diagnosis did not have plaque; this association was statistically significant. In the multivariate analysis, an association between periodontal disease and dementia was observed
in the crude analysis (OR = 4.43; 95% CI: 2.20–8.93; p = 0.000) and the adjusted analysis
(OR = 4.69; 95% CI: 2.32–9.48; p = 0.000). Conclusions: In conclusion, a significant relationship was identified between periodontal disease (assessed using the PSR system), the
presence of bacterial plaque, and gingival bleeding with dementia in the evaluated older
adults. This finding highlights the importance of periodontal health not only for oral wellbeing but also as a potentially modifiable risk factor for dementia prevention. Integrating
oral health interventions into broader geriatric care may contribute to delaying or reducing the risk of neurodegenerative diseases, underscoring the need for interdisciplinary
approaches in public health strategies.},
publisher = {MDPI},
keywords = {Illness},
keywords = {Periodontal disease},
keywords = {Age},
title = {Association of Periodontal Disease with Dementia in Older Adults from Lima, Peru},
doi = {10.3390/oral5040094},
author = {Ariza-Cabello, Leonardo and Lucar-Dueñas, Ximena and Noriega-Castañeda, Jorge and Gil Montoya, José Antonio and León Ríos, Ximena Alejandra},
}