@misc{10481/108126, year = {2025}, month = {12}, url = {https://hdl.handle.net/10481/108126}, abstract = {Response surface methodology using a central composite design was applied to optimize the accelerated solvent extraction (ASE) of phenolic compounds from avocado seed and seed coat by-products. The optimal extraction conditions for both matrices were achieved at 200 °C using as extractant solvent a mixture of ethanol:water (50,50, v/v). Additionally, the drying process was optimized for avocado seed samples at different temperatures (45, 55, 65, 75, and 85 °C). Changes in the phenolic profiles during the drying and extraction processed were monitorized using HPLC-TOF-MS. A total of 42 and 52 phenolic compounds were individually identified and quantified in avocado seed and seed coat, respectively. The optimal drying temperature for avocado seed was 85 °C. In contrast, the seed coat exhibited different optimal temperatures depending on the phenolic group under research, with 75 °C being the most favourable for the majority of compounds evaluated.}, organization = {Spanish Ministry of Economy and Competitiveness (MINECO, Project AGL2015-67995-C3-2)}, organization = {Diputación de Granada (Spain)}, organization = {Universidad Técnica Particular de Loja (Ecuador) (grants No. POA_VIN-56 and II CONV. 2019)}, organization = {Secretaría de Educación Superior, Ciencia, Tecnología e Innovación from Ecuador (SENESCYT) (grant 2015-AR7L7617)}, publisher = {Elsevier}, keywords = {Accelerated solvent extraction}, keywords = {Avocado seed}, keywords = {Avocado seed coat}, title = {Advanced recovery of bioactive polyphenols: integrated optimization of drying and green extraction for avocado seed by-products}, doi = {10.1016/j.fochx.2025.103216}, author = {Figueroa, Jorge G. and Borras Linares, María Isabel and Lozano Sánchez, Jesús and Quirantes-Piné, Rosa and Segura Carretero, Antonio}, }