@misc{10481/107895,
year = {2025},
month = {12},
url = {https://hdl.handle.net/10481/107895},
abstract = {This study focused on enhancing phenolic compounds recovery from mango leaves by using two non-thermal
methods: lactic acid bacteria fermentation and ultrasound-assisted extraction via sonotrode. Optimal ultrasound conditions were established using a Box-Behnken model and response surface methodology. The established conditions showed higher phenolic content extraction if compared with ultrasonic bath and Soxhlet (1.5
and 2 times, respectively). Fermentation with different lactic acid bacteria strains allowed determining 58 polar
compounds through HPLC-ESI-TOF-MS, including 11 compounds tentatively identified for the first time in
mango leaves. Combining both techniques significantly increased total phenolic compounds from 20 % to 52 %,
except with La. plantarum CECT 9567-C4. Antioxidant activity improved significatively by up to 7 % postfermentation with La. plantarum CECT 748 T. Additionally, Le. brevis CECT 5354 and La. plantarum CECT
9567-C4 also showed enhanced α-amylase inhibition, suggesting antidiabetic potential. Thus, fermentation
pretreatment with selected bacteria is able to produced phenolic-rich extracts with enhanced antioxidant and
antidiabetic activity from mango leaves. Further techno-economic and in vivo analyses will be necessary to
confirm these preliminary data.},
organization = {ERDF / Ministry of Science and Innovation - State Research Agency (project PID2022–141237OB-I00)},
organization = {MCIN/AEI/10.13039/501100011033/ - FEDER, EU (project RTI2018–099835-A-I00)},
organization = {Research Fellowships from the Government of Spain (FPU22/03192; FPU19/02009)},
publisher = {Elsevier},
keywords = {Mango leaves},
keywords = {By-products},
keywords = {Phenolic compounds},
title = {Evaluation of the potential to increase the recovery of phenolic compounds with antioxidant and antidiabetic activities from mango leaves by fermentation pre-treatment and ultrasound-assisted extraction via sonotrode},
doi = {10.1016/j.indcrop.2025.122125},
author = {Aznar Ramos, María José and De Montijo Prieto, Soumi and Razola-Díaz, María del Carmen and Martín-García, Beatriz and Jiménez Valera, María Manuela and Ruiz-Bravo López, Alfonso and Verardo, Vito and Gómez-Caravaca, Ana María},
}