@misc{10481/106851,
year = {2025},
month = {6},
url = {https://hdl.handle.net/10481/106851},
abstract = {In order to advance the practical applications of photoluminescence lanthanide-based nanoparticles (LnNPs), it is essential to minimize quenching by surface defects and to enhance the efficiency of lanthanide excitation. Surface functionalization with organic antennas has proven effective in preparing dye-sensitized LnNPs with enhanced photoluminescence performance. Nevertheless, the limited chemical and photochemical stability of the organic dyes hinders the practical applications of these composites. This report presents Eu-doped LaF3 submicron particles (EuLaSMDs) and analogue small nanoparticles (EuLaNPs) functionalized with a robust IrIII complex (Ir1) as antenna. The EuLaSMDs@Ir1 and EuLaNPs@Ir1 hybrids exhibit a combination of short-lived Ir-based (yellow) and long-lived Eu-based (red) emissions, which can be selectively detected by time-gated detection. Following Ir1-sensitization, the Eu-based emission is amplified, reaching up to 307-fold (for EuLaSMDs@Ir1) and 188-fold (for EuLaNPs@Ir1), compared to that exhibited by pristine phosphors. Efficient Ir1-sensitized EuIII-based emission can also be achieved using NIR excitation, as Ir1 exhibits a moderate cross-section of σ2 = 4.6 ± 0.6 GM at λ = 800 nm. Both hybrids demonstrate effective internalization in HEK-293 cells with no observed toxicity at concentrations relevant to biomedical applications. Cells are imaged by TG-imaging and PLIM microscopy. Following UV–vis (λexc = 375 nm) or NIR (λexc = 800 nm) excitation, overlapped Ir1- and Eu-based emissions are detected.},
publisher = {Wiley},
title = {Bright LaF3: Eu@ Ir Phosphors Combining Two‐Photon Excitation, d→ f Energy Transfer and Tunable Time‐Gated Chromaticity for Multicolor Cell Imaging},
doi = {10.1002/adom.202500717},
author = {Yating, Ye and Bramini, Mattia and Sánchez Moreno, Paola and Orte Gutiérrez, Ángel and Jiménez Gallego, Juan Ramón and Herrera Martínez, Juan Manuel},
}