@misc{10481/106836,
year = {2025},
month = {8},
url = {https://hdl.handle.net/10481/106836},
abstract = {Background: Children affected by unilateral cleft lip and palate (UCLP) represent a therapeutic challenge requiring the development of novel therapies, such as the implant of
a bioengineered tissue—BIOCLEFT—or the use of nasoalveolar molding (NAM). The
objective of this work was to evaluate the effects of NAM on the surgical and aesthetic
outcomes of children with UCLP. Methods: A total of 36 children with UCLP treated
at a craniofacial malformations management unit were evaluated, including 23 patients
treated with presurgical NAM followed by palate surgical correction (NAM group) and
13 patients treated surgically without previous NAM (non-NAM group). Measurements
were obtained from each patient immediately before palate surgery, including four linear
measurements: nasal ala projection length (NAPL), nasal dome height (NDH), superoinferior alar groove position (S-I AGP), and nasal dome position (M-L NDP), and two angular
measurements: columellar deviation (CD) and nasal bridge deviation (NBD). Results:
When NAM was used, a significant improvement of the basilar view linear measurements
of the patient’s nose was found, including the NAPL and NDH, and the frontal view linear
measurement M-L NDP, but not S-I AGP. Significant improvements were also observed
in the angular measurements of nasal symmetry CD and NBD. All these variables, except
the S-I AGP, significantly correlated with the treatment group, and two variables—NAPL
and CD—significantly contributed to generate a predictive model developed using binary
logistic regression. Conclusions: These findings support the use of NAM to efficiently
improve the nasal symmetry and the presurgical outcomes of patients with UCLP.},
organization = {Instituto de Salud Carlos III — Ministerio de Ciencia, Innovación y Universidades (España)
 (ICI19/00024, proyecto BIOCLEFT)},
organization = {European Regional Development Fund (FEDER/ERDF) — European Union},
publisher = {MDPI},
keywords = {nasoalveolar molding},
keywords = {unilateral cleft lip and palate},
keywords = {nasal symmetry},
title = {Evaluating the Effectiveness of Nasoalveolar Molding in the Management of Children with Unilateral Cleft Lip and Palate: A Cohort Study},
doi = {10.3390/dj13090394},
author = {España-Guerrero, Alba and España Guerrero, Enrique and Liceras Liceras, Esther and Bullejos Martínez, Elena and Martínez Plaza, Adoración and Alaminos Mingorance, Miguel and Fernández Valadés, Ricardo and España López, Antonio},
}