@misc{10481/106526,
year = {2025},
month = {9},
url = {https://hdl.handle.net/10481/106526},
abstract = {Background: Central sensitization syndromes (CSSs) are associated with a high incidence
of traumatic events; however, few studies have examined the potential mechanisms linking
post-traumatic stress disorder (PTSD) and pain. Objectives: The present research aims
to clarify this association by exploring the presence of trauma, PTSD, and related clinical
variables in participants with CSSs compared to healthy controls and those with medical
problems. Methods: A large sample of both sexes of the Spanish general population
(n = 1542; aged 18–84 years) completed an online survey assessing the presence of traumatic
experiences (psychological trauma, physical trauma, physical and sexual abuse), PTSD,
and other clinical measures (central sensitization, pain, sleep quality, anxiety, depression,
perceived stress, and emotional regulation). Results: The CSS group (n = 467) showed
a higher incidence of repeated trauma, PTSD, and dissociative symptoms compared to
the medical pathologies (n = 214) and healthy (n = 861) groups. The CSS group also
showed greater clinical impairment than the other groups, especially the CSS subgroup
with PTSD. In this subgroup, PTSD symptoms were significantly correlated with the
remaining clinical measures, and sleep dysfunction, pain catastrophizing, and emotional
dysregulation mediated the relationship between PTSD and pain, accounting for 55.3% of
the variance. Conclusions: CSS represents a major therapeutic challenge. An integrated
treatment addressing both trauma and pain, with an emphasis on sleep quality, pain
catastrophizing, and emotional regulation, could improve the effectiveness of the current
therapeutic approaches.},
organization = {MCIN/AEI/10.13039/501100011033 (project PID2019-109612GB-I00)},
publisher = {MDPI},
keywords = {Trauma},
keywords = {Post-traumatic stress disorder},
keywords = {Central sensitization syndromes},
title = {Central Sensitization Syndromes and Trauma: Mediating Role of Sleep Quality, Pain Catastrophizing, and Emotional Dysregulation Between Post-Traumatic Stress Disorder and Pain},
doi = {10.3390/healthcare13172221},
author = {Miró Morales, María Elena and Sánchez Gómez, Ana Isabel and Raya Terrón, Ada and Martínez Narváez-Cabeza de Vaca, María del Pilar},
}