@misc{10481/106077,
year = {2025},
month = {6},
url = {https://hdl.handle.net/10481/106077},
abstract = {Background/Objectives: To examine the association between body composition and glucose tolerance in young adults with normal weight, overweight, or obesity. Methods:
This observational case–control study included 154 healthy individuals aged 18–25 years.
Participants were categorized into three BMI-based groups and underwent anthropometric
and body composition assessments using bioelectrical impedance. Glucose tolerance was
evaluated via oral glucose tolerance testing, with capillary blood samples collected at
baseline and at 30, 60, 90, and 120 min post load. Results: Compared to the normal-weight
group, overweight and obese individuals exhibited significantly higher body weight, BMI,
visceral and total fat percentages, and reduced muscle mass. Obese participants also
showed a significantly greater glucose area under the curve (AUC) and higher fasting and
post-load glucose levels. Visceral fat was positively correlated with metabolic impairment.
These results indicate a progressive decline in glucose tolerance associated with increasing
adiposity and reduced lean mass. Conclusions: Young adults with elevated BMI already
demonstrate marked alterations in body composition and impaired glucose tolerance, even
in the absence of overt metabolic disease. These findings underscore the importance of
the early identification of at-risk individuals using simple, non-invasive tools. Preventive
strategies promoting healthy body composition in early adulthood may reduce the future
risk of diabetes and its associated complications.},
organization = {Ciudad Autónoma de Ceuta-UGR (CE-06-UGR24)},
publisher = {MDPI},
keywords = {Body Mass Index},
keywords = {Diabetes},
keywords = {glucose intolerance},
keywords = {Insulin resistance},
keywords = {Obesity},
title = {Impaired Glucose Tolerance and Altered Body Composition in Obese Young Adults: A Case–Control Study},
doi = {10.3390/biomedicines13071569},
author = {Mohamed Mohamed, Himan and Pardo Moreno, Teresa and Jimenez-Palomares, Margarita and Pérez Ardanaz, Bibiana and Sánchez-Lara, Encarnación and Vazquez-Lara, María D. and de la Mata Fernández, Mario and García-Morales, Victoria and Ramos Rodríguez, Juan José},
}