@misc{10481/105588,
year = {2025},
month = {6},
url = {https://hdl.handle.net/10481/105588},
abstract = {We describe a systematic analysis of non-aromatic fluorescence (NAF)-emitting peptides in solution and
show that short peptides derived from zwitterionic single α helices (SAHs), formed exclusively by nonaromatic lysine and glutamic acid residues, are UV active and luminescent at near-UV wavelengths in
solution (λexc = 320 nm; λem ≈ 420 nm). We also show that their emission depends on the α-helical
folding, which favors intramolecular through-space interactions between the Lys/Glu side chains, and
that conservative mutations, such as the replacement of Lys by Orn or Arg, strongly influence the NAF
emission},
organization = {MCIN/AEI/10.13039/501100011033 / ERDF (PID2021-127702NB-I00 and PID2020-114256RBI00)},
organization = {MCIN/AEI/10.13039/501100011033 and the European Union NextGenerationEU/PRTR (TED2021-131641B-C41)},
organization = {FEDER / Junta de Andalucía (P21_00212)},
organization = {Xunta de Galicia (ED431G 2023/03)},
organization = {Xunta de Galicia / ERDF (ED431C 2021/29)},
organization = {FCT/MCTES (PIDDAC)},
organization = {European Union’s Horizon 2020 (grant agreement no. 964593)},
publisher = {Elsevier},
title = {Non-aromatic fluorescence from single α-helical peptides},
doi = {10.1016/j.xcrp.2025.102631},
author = {González González, Carmen and López Blanco, Roi and González Vera, Juan Antonio and Melle Franco, Manuel and Orte Gutiérrez, Ángel and Vazquez, M. Eugenio},
}