@misc{10481/101868,
year = {2022},
url = {https://hdl.handle.net/10481/101868},
abstract = {Medical research is progressing to clarify the full spectrum of sub-acute and long-term effects of the post-COVID-19 syndrome. However, most manuscripts published to date only analyze the effects of post-COVID-19 in patients discharged from hospital, which may induce significant bias. Here, we propose a pioneering study to analyze the single and multiple associations between post-COVID-19 characteristics with up to 6-months of follow-up in hospitalized and non-hospitalized COVID-19 patients. The cohort study was conducted from May to October 2020 at the University Hospital Virgen de la Nieves, the leading hospital assigned for patients with COVID-19 in Granada, Spain. A total of 372 and 217 patients—with 217 and 207 included in the first and second follow-up visits—were referred 2 and 6 months after diagnosing COVID-19, respectively. We find out that post-COVID-19 clinical and mental health impairment symptoms are correlated with patient gender. Logistic adjustments showed strong statistically robust single and multiple associations of demographic, clinical, mental health, X-ray, laboratory indices, and pulmonary function variables. The functional lung tests are good predictors of chest CT imaging abnormalities in elderly patients. Bilateral lung involvement, subpleural reticulum, ground-glass opacity, peripheral lung lesions, and bronchiectasis were the most common findings of the high-resolution computed tomography images. Non-hospitalized patients suffer more severe thromboembolic events and fatigue than those hospitalized.},
keywords = {Post‐COVID‐19 Syndrome},
keywords = {Prospective Cohort},
keywords = {Pulmonary Function Tests},
keywords = {Chest CT Imaging},
keywords = {Mental Health},
keywords = {Clinical Associations},
keywords = {Statistical Modeling},
title = {On the single and multiple associations of COVID-19 post-acute sequelae: 6-month prospective cohort study},
doi = {10.1038/s41598-022-07433-8},
author = {Jiménez-Rodríguez, Beatriz María and Gutierrez-Fernandez, Jose and Ramos-Urbina, Eldis Maria and Romero-Ortiz, Ana Dolores and García-Flores, Paula Isabel and Santiago-Puertas, Maria Inmaculada and Martín-López, Maria José and Lopez-Milena, Genaro and Fabregas, Rene and Morales-Garcia, Concepcion},
}