@misc{10481/101461, year = {1997}, url = {https://hdl.handle.net/10481/101461}, abstract = {The use of specific synthetic RNA homopolymers as templates and short oligonucleotides as primers has allowed evidence of the existence of a reverse transcriptase-like activity in Trypanosoma cruzi, to be revealed. The RNA:DNA products derived from this reaction are of approximately 110 nucleotides in length. The enzyme has greater affinity for poly(rA)/oligo(dT) templates than for poly(rC)/oligo(dG) having a 20 mM Mg++ ion requirement. The detected reverse transcriptase-like activity is not affected by aphidicolin and ddTTP but is inhibited by actinomycin D, novobiocin, rifamycin SV and AZT.}, publisher = {ScienceDirect - Elsevier}, keywords = {Nuclease activity}, keywords = {Trypanosoma cruzi}, keywords = {LINEs}, title = {Reverse transcriptase-like activity in Trypanosoma cruzi}, doi = {10.1016/s0001-706x(96)00611-0}, author = {González, Clara and thomas, Maria del Carmen and Martín Molina, Francisco and Alcami, j and Alonso, Carlos and Lopez, Manuel Carlos}, }