@misc{10481/100390,
year = {2018},
month = {2},
url = {https://hdl.handle.net/10481/100390},
abstract = {A novel multiresidue method is proposed for the determination of 12 5-nitroimidazoles and their metabolites in fish roe samples using UHPLC-MS/MS. A salting-out assisted liquid-liquid extraction procedure was performed prior to sample analysis. The separation of compounds was accomplished using a C18 Zorbax Eclipse Plus column (50 mm × 2.1 mm, 1.8 µm) at 25 °C and a mobile phase consisting of 0.025% (v/v) aqueous formic acid and pure MeOH at a flow rate of 0.5 mL/min. Parameters involved in ionization and fragmentation were also optimized. The method was characterized in terms of linearity (R2 ≥ 0.9992), extraction efficiency (≥68.9%), repeatability (RSD ≤ 9.8%), reproducibility (RSD ≤ 13.9%) and trueness (recoveries ≥81.4%). Decision limits (CCα) and detection capabilities (CCβ) were obtained in the ranges 0.1–1.0 and 0.2–1.7 µg/kg, respectively.},
organization = {The authors gratefully acknowledge the financial support of the “Junta de Andalucía” (Proyecto de Excelencia Ref: P12-AGR-1647). Maykel Hernández-Mesa thanks the Plan Propio of the University of Granada for a pre-doctoral contract.},
keywords = {5-Nitroimidazoles},
keywords = {Fish roe samples},
keywords = {Salting-out assisted liquid-liquid extraction},
keywords = {Ultra-high performance liquid chromatography},
keywords = {Mass spectrometry},
title = {Simple and rapid determination of 5-nitroimidazoles and metabolites in fish roe samples by salting-out assisted liquid-liquid extraction and UHPLC-MS/MS},
doi = {10.1016/j.foodchem.2018.01.101},
author = {Hernández Mesa, Maykel and Cruces Blanco, María Carmen and García Campaña, Ana María},
}