@misc{10481/100144,
year = {1989},
url = {https://hdl.handle.net/10481/100144},
abstract = {The aim of this study was to characterize the effect of hyperglycemia experimentally induced by alloxan on Trichinella spiralis infection. Thirteen days after the intraperitoneal injection of 100mgr/kgr alloxan, animals were infected with about 500 larvae of Trichinella spiralis. The results were compared to a control group of infected animals not receiving alloxan. During the enteral phase of trichinellosis (5th days after infection) hyperglycemia (163±19 vs 105±3 mg/dl, p<0.05) did not affect significantly either the number of adult enteral worms or the serum level of Trichinella circulating antigens. During the muscular phase (47th days after infection) hyperglycemic animals showed a significantly higher number of muscle larvae per gram of diaphragm muscle and a higher antibody titre.
From these results we conclude that mild hyperglycemia aggravates Trichinella spiralis infection, mainly during the muscular phase; the effect of hyperglycemia is independent of the diabetogenic agent used (alloxan) which does not influence the degree of Trichinella infection.},
publisher = {Consejo Superior de Investigaciones Cientificas Press (Tanner CE, Martinez-Fernandez AR, Bolas-Fernandez F)},
title = {Effect of hyperglycemia on the antigenic and antibody response to infection by Trichinella spiralis},
author = {Gomez Garcia, V and Rodriguez Osorio, M and Rodriguez, E and Castillo, M and García Espona, Juan Ignacio},
}