TY  - JOUR 
AU  - Estupiñán, Óscar
AU  - Ayllon Cases, Verónica
AU  - Ramos Mejía, Verónica
PY  - 2023
UR  - https://hdl.handle.net/10481/82677
AB  - Osteosarcomas are frequently associated to a poor prognosis and a modest response to current treatments. EC-
8042 is a well-tolerated mithramycin analog that has demonstrated an efficient ability to eliminate tumor
cells, including cancer stem cell...
LA  - eng
PB  - Elsevier
KW  - NOTCH1
KW  - HES1
KW  - EC-8042
KW  - Mithramycin
KW  - Sarcoma
KW  - Osteosarcoma
KW  - Cancer stem cells
TI  - Abrogation of stemness in osteosarcoma by the mithramycin analog EC-8042 is mediated by its ability to inhibit NOTCH-1 signaling
DO  - 10.1016/j.biopha.2023.114627
ER  -