TY  - JOUR 
AU  - Martínez Bueno, Manuel
AU  - Alarcón Riquelme, Marta Eugenia
PY  - 2019
UR  - http://hdl.handle.net/10481/59528
AB  - The importance of low frequency and rare variation in complex disease genetics
is difficult to estimate in patient populations. Genome-wide association studies are
therefore, underpowered to detect rare variation. We have used a combined...
LA  - eng
PB  - Frontiers Media
KW  - Systemic lupus erythematosus
KW  - Imputated rare variation
KW  - Sequence kernel association test
KW  - Aggregated case-control enrichment
TI  - Exploring Impact of Rare Variation in Systemic Lupus Erythematosus by a Genome Wide Imputation Approach
DO  - 10.3389/fimmu.2019.00258
ER  -