Deep Eutectic Solvents and Multicomponent Reactions: Two Convergent Items to Green Chemistry Strategies García Calvo Flores, Francisco Mingorance Sánchez, Cristina Alternative solvents Biocompatible solvents Deep eutectic solvents Green chemistry Sustainability One of the highlights of green chemistry is the development of techniques and procedures with low environmental impact. In the last years, deep eutectic solvents (DES) have become an important alternative to conventional organic solvents. For a period ionic liquids have provoked remarkable interest, but they have been displaced by DES because they show easier preparation methods, lower prices, many of them are biodegradable and compatible with biological systems. In addition, they show adjustable physicochemical properties, high thermal stability, low volatility and are compatible with water. In this paper is reviewed the state of the art of the use of DES paying special attention to the role of reaction media in organic synthesis. 2021-10-08T06:26:02Z 2021-10-08T06:26:02Z 2021-08-17 info:eu-repo/semantics/article F. G. Calvo-Flores, C. Mingorance-Sánchez, ChemistryOpen 2021, 10, 815. [doi.org/10.1002/open.202100137] http://hdl.handle.net/10481/70729 10.1002/open.202100137 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España Wiley-VCH Verlag GmbH