Specific Ion Effects in Cholesterol Monolayers
Metadatos
Afficher la notice complèteAuteur
Castillo Santaella, Teresa del; Maldonado Valderrama, Julia; Faraudo Gener, Jordi; Martín-Molina, AlbertoEditorial
MDPI
Materia
Ionic specificity Cholesterol Langmuir monolayers Molecular dynamics simulations Surface forces
Date
2016Referencia bibliográfica
Castillo-Santaella, T. [et al]. A. Specific Ion Effects in Cholesterol Monolayers. Materials 2016, 9, 340. [http://hdl.handle.net/10481/45003]
Résumé
The interaction of ions with interfaces and, in particular, the high specificity of these interactions to the particular ions considered, are central questions in the field of surface forces. Here we study the effect of different salts (NaI, NaCl, CaCl2 and MgCl2) on monolayers made of cholesterol molecules, both experimentally (surface area vs. lateral pressure isotherms measured by a Langmuir Film Balance) and theoretically (molecular dynamics (MD) all-atomic simulations). We found that surface isotherms depend, both quantitatively and qualitatively, on the nature of the ions by altering the shape and features of the isotherm. In line with the experiments, MD simulations show clear evidences of specific ionic effects and also provide molecular level details on ion specific interactions with cholesterol. More importantly, MD simulations show that the interaction of a particular ion with the surface depends strongly on its counterion, a feature ignored so far in most theories of specific ionic effects in surface forces.