A standalone version of IsoFinder for the computational prediction of isochores in genome sequences
Identificadores
URI: http://hdl.handle.net/10481/33381Metadatos
Mostrar el registro completo del ítemMateria
Bioinformatics IsoFinder Isochores Genomics DNA sequences Chromosome maps
Fecha
2008Patrocinador
The IsoFinder project was supported by the Spanish Government (Grant No. BIO2005-09116-C03-01) and the Spanish Junta de Andalucía (Grants No. P06-FQM-01858, P07-FQM3163 and CVI-162).Resumen
Isochores are long genome segments relatively homogeneous in G+C. A heuristic algorithm based on entropic segmentation has been developed by our group, and a web server implementing all the required components is available. However, a researcher may want to perform batch processing of many sequences simultaneously in its local machine, instead of analyzing them on one by one basis through the web. To this end, standalone versions are required. We report here the implementation of two standalone programs, able to predict isochores at the sequence level: 1) a command-line version (IsoFinder) for Windows and Linux systems; and 2) a user-friendly version (IsoFinderWin) running under Windows.