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A specific protein-enriched enteral formula decreases cortisolemia and improves plasma albumin and amino acid concentrations in elderly patients
dc.contributor.author | Olza Meneses, Josune | |
dc.contributor.author | Mesa García, María Dolores | |
dc.contributor.author | Poyatos Martínez, Rafael Miguel | |
dc.contributor.author | Aguilera García, Concepción María | |
dc.contributor.author | Moreno-Torres, Rosario | |
dc.contributor.author | Pérez, Milagros | |
dc.contributor.author | Pérez De La Cruz, Antonio Jesús | |
dc.contributor.author | Gil Hernández, Ángel | |
dc.date.accessioned | 2014-06-27T13:14:38Z | |
dc.date.available | 2014-06-27T13:14:38Z | |
dc.date.issued | 2010 | |
dc.identifier.citation | Olza, J.; et al. A specific protein-enriched enteral formula decreases cortisolemia and improves plasma albumin and amino acid concentrations in elderly patients. Nutrition and Metabolism, 7: 58 (2010). [http://hdl.handle.net/10481/32398] | es_ES |
dc.identifier.issn | 1743-7075 | |
dc.identifier.uri | http://hdl.handle.net/10481/32398 | |
dc.description.abstract | [Background] Old age is associated with an involuntary and progressive but physiological loss of muscle mass. The aim of this study was to evaluate the effects of exclusive consumption for 6 months of a protein-enriched enteral diet with a relatively high content of branched-chain amino acids on albuminemia, cortisolemia, plasma amino acids, insulin resistance, and inflammation biomarkers in elderly patients. [Methods] Thirty-two patients from the Clinical Nutrition Outpatient Unit at our hospital exclusively consumed a protein-enriched enteral diet for 6 months. Data were collected at baseline and at 3 and 6 months on anthropometric and biochemical parameters and on plasma concentrations of amino acids, cortisol, adrenocorticotropic hormone, urea, creatinine, insulin resistance, and inflammation biomarkers. [Results] The percentage of patients with albumin concentration below normal cut-off values decreased from 18% to 0% by the end of the study. At 6 months, concentrations of total plasma (p = 0.008) and essential amino acids (p = 0.011), especially branched-chain amino acids (p = 0.031), were higher versus baseline values, whereas 3-methylhistidine (p = 0.001), cortisol (p = 0.001) and adrenocorticotropic hormone (p = 0.004) levels were lower. [Conclusions] Regular intake of specific protein-enriched enteral formula increases plasma essential amino acids, especially branched-chain amino acids, and decreases cortisol and 3-methylhistidine, while plasma urea and creatinine remain unchanged. | es_ES |
dc.description.sponsorship | This study was financed by Vegenat S.A. Vegenat S.A. has designed the new formula for EN. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Biomed Central | es_ES |
dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | es_ES |
dc.subject | Muscle mass | es_ES |
dc.subject | Performance | es_ES |
dc.subject | Ingestion | es_ES |
dc.subject | Men | es_ES |
dc.subject | Strength | es_ES |
dc.subject | Hormones | es_ES |
dc.subject | Humans | es_ES |
dc.subject | Women | es_ES |
dc.subject | Age | es_ES |
dc.title | A specific protein-enriched enteral formula decreases cortisolemia and improves plasma albumin and amino acid concentrations in elderly patients | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.doi | 10.1186/1743-7075-7-58 |