@misc{10481/87399,
year = {2019},
month = {10},
url = {https://hdl.handle.net/10481/87399},
abstract = {Just as “Deconstructivism”appearedas anovel movement in archi-tecturein the 1980s,deconstructiveapproaches haverecentlyemergedas excellentstrategiesfor scaffoldhoppingmodificationsin chemistry.The deconstructionand functionalizationof cyclicmoleculesmainlyinvolvesthe cleavageof the carbon–carbon(C@C) bondfollowedbythe constructionof new bonds.The cleavageof inertC@Csinglebonds,especiallyin unstrainedcycles,and theirsubsequentfunctionalizationis still one of the mostsought-afterchallengesin chemistry.Inthis vein,radical-mediatedstrategiesprovidean excellentapproachforachievingthis aim.Thisminireviewis an outlineof the historyofhomolyticcleavageand highlightsthe recentadvancesin exploringnewchemicalspaceby deconstructivefunctionalization.},
organization = {MINECO for the IJCI-2017-31674 contract.},
publisher = {Wiley Online Library},
title = {Radical‐promoted C‐C bond cleavage: a deconstructive approach for selective functionalization},
doi = {10.1002/anie.201905218},
author = {Morcillo Martínez, Sara Patricia},
}