@misc{10481/86316,
year = {2023},
month = {11},
url = {https://hdl.handle.net/10481/86316},
abstract = {Endocrine disrupting chemicals (EDCs) are exogenous substances widely disseminated
both in the environment and in daily-life products which can interfere with the regulation and
function of the endocrine system. These substances have gradually entered the food chain, being
frequently found in human blood and urine samples. This becomes a particularly serious issue
when they reach vulnerable populations such as pregnant women, whose hormones are more
unstable and vulnerable to EDCs. The proper formation and activity of the placenta, and therefore
embryonic development, may get seriously affected by the presence of these chemicals, augmenting
the risk of several pregnancy complications, including intrauterine growth restriction, preterm birth,
preeclampsia, and gestational diabetes mellitus, among others. Additionally, some of them also exert
a detrimental impact on fertility, thus hindering the reproductive process from the beginning. In
several cases, EDCs even induce cross-generational effects, inherited by future generations through
epigenetic mechanisms. These are the reasons why a proper understanding of the reproductive
and gestational alterations derived from these substances is needed, along with efforts to establish
regulations and preventive measures in order to avoid exposition (especially during this particular
stage of life).},
organization = {Universidad de Granada
 PP2022.PP-07},
organization = {Ministry of Education of Spain  FPU21/04865},
publisher = {MDPI},
keywords = {Endocrine disrupting chemical},
keywords = {Pregnancy},
keywords = {Gestation},
keywords = {Complications},
keywords = {Maternal-fetal health},
keywords = {Fertility},
keywords = {Bisphenols},
keywords = {Phthalates},
keywords = {Pesticides},
keywords = {Advanced maternal age},
title = {The Role of Endocrine Disrupting Chemicals in Gestation and Pregnancy Outcomes},
doi = {10.3390/nu15214657},
author = {Puche Juárez, María and Toledano, Juan M. and Moreno Fernández, Jorge and Gálvez Ontiveros, Yolanda and Rivas Velasco, Ana María and Díaz Castro, Javier and Ochoa Herrera, Julio José},
}