@misc{10481/55762,
year = {2019},
month = {3},
url = {http://hdl.handle.net/10481/55762},
abstract = {The prognostic nutritional index (PNI), controlling nutritional status (CONUT) score and
nutritional risk index (NRI) have been described as useful screening tools for patient prognosis in
several diseases. The aim of this study was to examine the relationship between PNI, CONUT and
NRI with clinical disease activity and damage in 173 patients with systemic lupus erythematous (SLE).
Disease activity was assessed with the SLE disease activity index (SLEDAI-2K), and disease-related
organ damage was assessed using the SLICC/ACR damage index (SDI) damage index. PNI and NRI
were significantly lower in active SLE patients than in inactive SLE patients (p < 0.001 and p = 0.012,
respectively). PNI was inversely correlated with the SLEDAI score (p < 0.001) and NRI positively
correlated with SLEDAI and SDI scores (p = 0.027 and p < 0.001). Linear regression analysis adjusting
for age, sex and medications showed that PNI was inversely correlated with SLEDAI (  (95% CI) =
-0.176 (-0.254, -0.098), p < 0.001) and NRI positively correlated with SLEDAI (  (95% CI) = 0.056
(0.019, 0.093), p = 0.003) and SDI (  (95% CI) = 0.047 (0.031, 0.063), p < 0.001). PNI (odds ratio (OR)
0.884, 95% confidence interval (CI) 0.809–0.967, p = 0.007) and NRI ((OR) 1.067, 95% CI 1.028–1.108,
p = 0.001) were independent predictors of active SLE. These findings suggest that PNI and NRI may
be useful markers to identify active SLE in clinical practice.},
organization = {This study was supported by the grant PI0523-2016 from “Consejería de igualdad, salud y políticas
sociales” (Junta de Andalucía) and is part of the research group LyDIMED “Lupus y Dieta Mediterránea”.
G. Pocovi-Gerardino is a predoctoral fellow from the doctoral program “Medicina clínica y salud pública” of the
University of Granada},
publisher = {MDPI},
keywords = {Prognostic nutritional index},
keywords = {Controlling nutritional status},
keywords = {Nutritional risk index},
keywords = {Systemic lupus erythematosus},
keywords = {Lupus disease activity},
keywords = {Lupus damage},
title = {The Prognostic Nutritional Index and Nutritional Risk Index Are Associated with Disease Activity in Patients with Systemic Lupus Erythematosus},
doi = {10.3390/nu11030638},
author = {Correa Rodríguez, María and Pocovi-Gerardino, Gabriela and Callejas Rubio, José Luis and Ríos Fernández, Raquel and Martín-Amada, María and Cruz-Caparros, María-Gracia and Ortego-Centeno, Norberto and Rueda Medina, Blanca María},
}